Fifteen crude extracts from the stem bark and seeds of four medicinal plants, viz:
Entandrophragma angolense
,
Picralima nitida
,
Schumanniophyton magnificum
and
Thomandersia hensii
were tested
in vitro for their antimalarial activity against the chloroquine-resistant
Plasmodium falciparum
W2 strain. The results showed that the extracts of these plants possessed some antimalarial activity, the methanol extract of
Picralima nitida demonstrating the highest activity in vitro. Further isolation and identification of some active compounds from these plants will justify their common use in traditional medicine for the treatment of malaria or fever in Cameroon.
