Ethyl acetate(EA) extract of the stem bark of
Cylicodiscus gabunensis
(CG) was analysed phytochemically and evaluated for its antimicrobial activity against 17 pathogenic species isolated from patient:
Escherichia coli
,
Klebsiella pneumoniae
,
Shigella dysenteriae
,
Shigella flexneri
,
Morganella morganii
,
Proteus vulgaris
,
Proteus mirabilis
,
Salmonella typhi
,
Citrobacter freundii
,
Enterobacter cloacae
,
Enterobacter agglomerans
,
Staphylococcus aureus
,
Streptococcus feacalis
,
Pseudomonas aeruginosa
,
Bacillus cereus
,
Candida albicans
and
Candida glabrata
. Flavonoids, saponins, tannins, polyphenols, coumarins, triterpenes and/or sterols and reducing sugars were detected in the (EA) extract of CG. The best MIC and MBC values for the microorganisms sensitive to the extract were 0.00078 and 0.00315 mg/ml respectively. The greater and remarkable antimicrobial activity of the (EA) extract of CG was recorded with
Staphylococcus aureus
,
Proteus vulgaris and
Bacillus cereus T. These results provide a rationalization for the traditional use of this plant for the treatment of infections diseases.