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African Journal of Traditional, Complementary and Alternative Medicines
African Ethnomedicines Network
ISSN: 0189-6016
Vol. 14, No. 3, 2017, pp. 194-198
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Bioline Code: tc17096
Full paper language: English
Document type: Research Article
Document available free of charge
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African Journal of Traditional, Complementary and Alternative Medicines, Vol. 14, No. 3, 2017, pp. 194-198
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ANTI-VIRAL EFFECT OF HERBAL MEDICINE KOREAN TRADITIONAL CYNANCHUM PANICULATUM  (BGE.) KITAG EXTRACTS
Kim, Woong; Oh, Tae-Seok & Park, Youn-Jin
Abstract
Background: Pestiviruses in general, and Bovine Viral Diarrhea (BVD) in particular, present several potential targets
for directed antiviral therapy.
Material and Methods: The antiviral effect of Cynanchum paniculatum (Bge.) Kitag (Dog strangling vine: DS)
extract on the bovine viral diarrhea (BVD) virus was tested. First, a cytotoxicity test in MDBK (Madin-Darby bovine
kidney) cells was done with all organic extract concentrations.
Results: The cytotoxic concentration CC50 for the ethyl acetate (EA) extracts was 18.2 ug/ml. In the tissue culture,
infectious dose (TCID50) assay, the BVD virus decreased when treated with 18.2 ug/ml of the ethyl acetate extracts.
Conclusion: Ethyl acetate extracts and fractions of the DS extract could be used as a potential antiviral for BVD.
Keywords
Antiviral; Bovine viral diarrhoea(BVD) virus; Cynanchum paniculatum (Bge.) Kitag.Ethly acetate extract
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Alternative site location: http://journals.sfu.ca/africanem/index.php/ajtcam
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